The New John Gill Exposition of the Entire BibleGenesis 22:18
And in thy seed shall all nations of the earth be blessed,
&c.] That is, in his one and principal seed, the Messiah, that should
spring from him, (Galatians 3:16) , in whom all the elect of God, of all nations
under the heavens, are blessed with all spiritual blessings, with
peace, pardon, righteousness, and eternal life, with grace here and
glory hereafter; (See Gill on 12:3); or, "shall bless themselves"
F15 in him; or, "account themselves blessed"; apply to him for
blessings, claim their interest in them, and glory in them, and make
their boast of them:
because thou hast obeyed my voice;
in taking his son and offering him
up unto him, as much as he was permitted to do; and thus honouring God
by his obedience to him, he of his grace and goodness honours him with
the promise of being the father of multitudes, both in a literal and
spiritual sense, and with being the ancestor of the Messiah, in whom
all the blessings of grace and goodness meet.
F15 (wkrbth) "benedicent se", Munster; to the same purpose Vatablus,
Tigurine version, Piscator.