come out from among them
(1) Separation in Scripture is twofold: "from" whatever is contrary to the mind of God; and "unto" God Himself. The underlying principle is that in a moral universe it is impossible for God to fully bless and use His children who are in compromise or complicity with evil. The unequal yoke is anything which unites a child of God and an unbeliever in a common purpose Deuteronomy 22:10.
(2) Separation from evil implies (a) separation in desire, motive, and act, from the world, in the ethically bad sense of this present world-system. (See Scofield "Revelation 13:8") and (b) separation from believers, especially false teachers, who are "vessels unto dishonour" 2 Timothy 2:20,21; 2 John 1:9-11.
(3) Separation is not from contact with evil in the world or the church, but from complicity with and conformity to John 17:15; 2 Corinthians 6:14-18; Galatians 6:1.
(4) The reward of separation is the full manifestation of the divine fatherhood 2 Corinthians 6:17,18 unhindered communion and worship Hebrews 13:13-15 and fruitful service 2 Timothy 2:21 as world-conformity involves the loss of these, though not of salvation. Here, as in all else, Christ is the model. He was "holy, harmless, undefiled, and separate from sinners" Hebrews 7:26 and yet in such contact with them for their salvation that the Pharisees, who illustrate the mechanical and ascetic conception of separation (See Scofield "Matthew 3:7") , judged Him as having lost His Nazarite character. Luke 7:39 Cf ; 1 Corinthians 9:19-23; 10:27.