A musical instrument, probably composed of a number of pipes, mentioned Daniel 3:5,7,10,15.
In Matthew 9:23,24, notice is taken of players on the flute, here called "minstrels" (but in RSV "flute-players").
Flutes were in common use among the ancient Egyptians.
These dictionary topics are from M.G. Easton M.A., D.D., Illustrated Bible Dictionary, Third Edition, published by Thomas Nelson, 1897. Public Domain, copy freely.
Easton, Matthew George. "Entry for 'Flute'". "Easton's Bible Dictionary".