Probably the same with Circesium or Circusium, a fortified city on the west of the Euphrates, where the river Chaboras enters it. In Isaiah 10:9, it appears as taken by some king of Assyria. It was attacked by Pharaohnecho king of Egypt, near the close of king Josiah’s reign, 2 Chronicles 35:20. Five years afterwards Necho was signally defeated by Nebuchadnezzar, Jeremiah 46:1-12. In later times was held as a frontier post of the Roman empire on the east.
These dictionary topics are from American Tract Society Bible Dictionary published in 1859. Public Domain, copy freely.
Rand, W. W. "Entry for 'CARCHEMISH'". "American Tract Society Bible Dictionary".